Researchers found consuming eight cups per day causes a reduction in the types of neurotransmitters affected by cannabis; suggesting something in the drink may suppress the endocannabinoid system’s efficacy
Coffee has long been touted to have health benefits—claims range from somewhat credible to dubious. But as it turns out, our daily java jolt may have more of an effect on us that we previously thought.
According to a 2018 study published in the Journal of Internal Medicine that sought to “identify individual metabolite changes in response to coffee,” our morning fix has a far greater effect on our metabolism than previously believed.
The study asked 47 regular coffee drinkers to refrain from consuming the drink for a month, followed by the consumption of four cups a day the next month. For the 30 days after that, participants knocked back eight cups of daily brew. Blood samples were taken and results monitored for the duration of the study so researchers could analyze biochemical changes that occurred as a result of consuming the beverage.
Researchers found that consuming eight cups per day causes a reduction in the types of neurotransmitters affected by cannabis–suggesting that something in the drink may suppress the endocannabinoid system’s efficacy.
When stressed, the human body generally reduces the production of endocannabinoids. These results are forcing scientists to explore the possibility of a correlation between coffee consumption and the mechanics of adapting to change.
“The increased coffee consumption over the two-month span of the trial may have created enough stress to trigger a decrease in metabolites in this system,” said lead author Marilyn Cornelis of Northwestern University Feinberg School of Medicine upon publication of the study. “It could be our bodies’ adaptation to try to get stress levels back to equilibrium.”
Researchers reported that “a total of 115 metabolites were significantly associated with coffee intake. “These are entirely new pathways by which coffee might affect health,” said Cornelis. “Now we want to delve deeper and study how these changes affect the body.”
Scientists say more research is needed to define if and how this information can benefit users. “The novel metabolites and candidate pathways we have identified may provide new insight into the mechanisms by which coffee may be exerting its health effects,” the study concludes.
Want to keep up to date on what’s happening in the world of cannabis? Subscribe to the Cannabis Post newsletter for weekly insights into the industry, what insiders will be talking about and content from across the Postmedia Network.